Detection of Exosomal Cargoes by Plasmonic Biosensing Technology
Extracellular vesicles (EVs) are like tiny packages that cells release into the space around them. There are three kinds of these EVs - exosomes, microvesicles, and apoptotic bodies. Exosomes are released by almost all cell types...
Computational simulation for TiN quantum plasmonic biosensor
Understanding the molecular interaction between the receptors and TiN surface leading to successful functionalization and subsequent biosensing is the most significant attribute of computational modeling...
Single CRP antigen detection with TiN plasmonic biosensor
CRP is a typical indicator of body tissue inflammation. Its molecular weight is about 115KDa, CRP antigen is detected to concentration of 3.26 aM (atto molar, i.e. 3.26E-18 mole per liter or about 2,000 copies per milliliter). Since our liquid sample volume is 0.36 milliliter, that is about 720 CRP antigen molecules in total, or 5 CRP molecules in every microwell.
Detection of novel coronaviruses by QPLoC biosensor with CRISPR-Cas13 technology
Herein, we employ the CRISPR-Cas13 genetic editing technology with corresponding combinations of crRNA to split the SARS-CoV-2 viral spike genome into fragments. Thereafter, these fragments are detected by direct hybridization with complementary RNA probes by thermoplasmonic heating and quantum optical measurements...